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    Rgsl1 regulator of G-protein signaling like 1 [ Mus musculus (house mouse) ]

    Gene ID: 240816, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rgsl1provided by MGI
    Official Full Name
    regulator of G-protein signaling like 1provided by MGI
    Primary source
    MGI:MGI:2685048
    See related
    Ensembl:ENSMUSG00000042641 AllianceGenome:MGI:2685048
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm202; Rgsl2; 4930415K13Rik
    Summary
    Orthologous to human RGSL1 (regulator of G protein signaling like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 2.3), cortex adult (RPKM 0.6) and 2 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rgsl1 in Genome Data Viewer
    Location:
    1 G3; 1 65.43 cM
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (153653675..153723087, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (153777929..153847341, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:155593298-155593499 Neighboring gene STARR-positive B cell enhancer ABC_E5824 Neighboring gene STARR-positive B cell enhancer ABC_E9185 Neighboring gene STARR-positive B cell enhancer mm9_chr1:155598826-155599127 Neighboring gene regulator of G-protein signaling 16 Neighboring gene ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) Neighboring gene predicted gene, 41974 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:155689311-155689530 Neighboring gene zinc finger protein 799 pseudogene Neighboring gene transmembrane epididymal family member 2 Neighboring gene transmembrane epididymal protein 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    regulator of G-protein signaling protein-like
    Names
    regulator of G-protein signaling 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243223.1 → NP_001230152.1  regulator of G-protein signaling protein-like isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC157793, AK029630, AK161463, CJ042418
      Consensus CDS
      CCDS56645.1
      UniProtKB/TrEMBL
      H3BL40, V9GXV7
      Related
      ENSMUSP00000135642.2, ENSMUST00000124558.10
      Conserved Domains (2) summary
      cd08728
      Location:649 → 826
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
      cl02565
      Location:873 → 982
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    2. NM_001368270.1 → NP_001355199.1  regulator of G-protein signaling protein-like isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC099702, AC154140, AC157793
      Consensus CDS
      CCDS87893.1
      UniProtKB/TrEMBL
      A0A5F8MPV0, V9GXV7
      Related
      ENSMUSP00000159120.2, ENSMUST00000238926.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      153653675..153723087 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529577.4 → XP_006529640.1  regulator of G-protein signaling protein-like isoform X3

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (2) summary
      cd08728
      Location:675 → 852
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
      cl02565
      Location:899 → 1008
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    2. XM_006529574.3 → XP_006529637.1  regulator of G-protein signaling protein-like isoform X1

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (2) summary
      cd08728
      Location:711 → 888
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
      cl02565
      Location:935 → 1044
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    3. XM_006529576.5 → XP_006529639.1  regulator of G-protein signaling protein-like isoform X2

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (2) summary
      cd08728
      Location:690 → 867
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
      cl02565
      Location:914 → 1023
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    4. XM_011248001.3 → XP_011246303.1  regulator of G-protein signaling protein-like isoform X6

      See identical proteins and their annotated locations for XP_011246303.1

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (2) summary
      cd08728
      Location:582 → 759
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
      cl02565
      Location:806 → 915
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    5. XM_036164772.1 → XP_036020665.1  regulator of G-protein signaling protein-like isoform X5

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (2) summary
      cd08728
      Location:608 → 785
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
      cl02565
      Location:832 → 941
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    6. XM_017320546.3 → XP_017176035.1  regulator of G-protein signaling protein-like isoform X4

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (2) summary
      cd08728
      Location:629 → 806
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
      cl02565
      Location:853 → 962
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    7. XM_006529579.2 → XP_006529642.1  regulator of G-protein signaling protein-like isoform X6

      See identical proteins and their annotated locations for XP_006529642.1

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (2) summary
      cd08728
      Location:582 → 759
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2
      cl02565
      Location:806 → 915
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    8. XM_011248002.4 → XP_011246304.1  regulator of G-protein signaling protein-like isoform X7

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (1) summary
      cd08728
      Location:711 → 888
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2

    9. XM_036164776.1 → XP_036020669.1  regulator of G-protein signaling protein-like isoform X8

      UniProtKB/TrEMBL
      V9GXV7
      Conserved Domains (1) summary
      cd08728
      Location:711 → 888
      RGS-like_2; Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2

    10. XM_006529582.3 → XP_006529645.1  regulator of G-protein signaling protein-like isoform X9

    11. XM_017320549.1 → XP_017176038.1  regulator of G-protein signaling protein-like isoform X10

    12. XM_017320550.1 → XP_017176039.1  regulator of G-protein signaling protein-like isoform X11

    13. XM_017320548.1 → XP_017176037.1  regulator of G-protein signaling protein-like isoform X10

    Nucleotide Protein Strain
    Heading Accession and Version

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