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    Tada1 transcriptional adaptor 1 [ Mus musculus (house mouse) ]

    Gene ID: 27878, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tada1provided by MGI
    Official Full Name
    transcriptional adaptor 1provided by MGI
    Primary source
    MGI:MGI:1196415
    See related
    Ensembl:ENSMUSG00000026563 AllianceGenome:MGI:1196415
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Staf42; Tada1l; D1Ertd251e; 2900026B15Rik
    Summary
    Predicted to enable transcription coactivator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; focal adhesion; and nucleoplasm. Predicted to be part of SAGA complex. Is expressed in several structures, including alimentary system; brain; connective tissue; genitourinary system; and hemolymphoid system. Orthologous to human TADA1 (transcriptional adaptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 23.4), CNS E14 (RPKM 21.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Tada1 in Genome Data Viewer
    Location:
    1 H2.3; 1 73.74 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (166206736..166221190)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (166379167..166393621)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_02926 Neighboring gene maelstrom spermatogenic transposon silencer Neighboring gene immunoglobulin-like domain containing receptor 2 Neighboring gene STARR-positive B cell enhancer mm9_chr1:168290436-168290736 Neighboring gene STARR-seq mESC enhancer starr_02930 Neighboring gene STARR-positive B cell enhancer ABC_E11695 Neighboring gene pogo transposable element with KRAB domain Neighboring gene STARR-seq mESC enhancer starr_02931 Neighboring gene ubiquinol-cytochrome c reductase subunit pseudogene Neighboring gene predicted gene, 39694

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transcription coactivator activity  
    enables transcription coactivator activity  
    enables transcription coactivator activity  
    Component Evidence Code Pubs
    part_of SAGA complex  
    part_of SAGA complex  
    part_of SAGA complex PubMed 
    located_in cytosol  
    located_in cytosol  
    located_in focal adhesion  
    located_in focal adhesion  
    located_in nucleoplasm  
    located_in nucleoplasm  
    located_in nucleus  

    General protein information

    Preferred Names
    transcriptional adapter 1
    Names
    transcriptional adapter 1-like protein
    transcriptional adaptor 1 (HFI1 homolog, yeast) like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030245.3NP_084521.1  transcriptional adapter 1

      See identical proteins and their annotated locations for NP_084521.1

      Status: VALIDATED

      Source sequence(s)
      AC161807, AK151132, BY057637, DV645054
      Consensus CDS
      CCDS15450.1
      UniProtKB/Swiss-Prot
      Q99LM9
      Related
      ENSMUSP00000027846.8, ENSMUST00000027846.8
      Conserved Domains (1) summary
      pfam12767
      Location:7193
      SAGA-Tad1; Transcriptional regulator of RNA polII, SAGA, subunit

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      166206736..166221190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030254784.2XP_030110644.1  transcriptional adapter 1 isoform X1

      Conserved Domains (1) summary
      pfam12767
      Location:251
      SAGA-Tad1; Transcriptional regulator of RNA polII, SAGA, subunit
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