Slc5a4 solute carrier family 5 member 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Slc5a4provided by RGD
Full Name: solute carrier family 5 member 4provided by RGD
Primary source: RGD:1306923
See related: EnsemblRapid:ENSRNOG00000049734 AllianceGenome:RGD:1306923
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Slc5a4a
Summary: Enables proton transmembrane transporter activity. Acts upstream of or within proton transmembrane transport. Predicted to be active in plasma membrane. Orthologous to human SLC5A4 (solute carrier family 5 member 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 3.0), Uterus (RPKM 0.6) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 20p12

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (12475096..12518186, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (12475644..12518738, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (13415039..13458110, complement)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables D-glucose:sodium symporter activity	IBA Inferred from Biological aspect of Ancestor more info
NOT enables D-glucose:sodium symporter activity	ISO Inferred from Sequence Orthology more info
enables D-glucose:sodium symporter activity	ISO Inferred from Sequence Orthology more info
enables low-affinity D-glucose:sodium symporter activity	ISO Inferred from Sequence Orthology more info
enables proton transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables proton transmembrane transporter activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in D-glucose transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in hexose transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within proton transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within proton transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in sodium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in sodium ion transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: solute carrier family 5 member 4

Names: low affinity sodium-glucose cotransporter; low affinity sodium-glucose cotransporter-like; solute carrier family 5 (glucose activated ion channel), member 4; solute carrier family 5 (low affinity glucose cotransporter), member 4; solute carrier family 5 (low affinity glucose cotransporter), member 4a; solute carrier family 5, member 4a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.