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    Ttc29 tetratricopeptide repeat domain 29 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291944, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ttc29provided by RGD
    Official Full Name
    tetratricopeptide repeat domain 29provided by RGD
    Primary source
    RGD:1589777
    See related
    EnsemblRapid:ENSRNOG00000012342 AllianceGenome:RGD:1589777
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cilium movement and cilium organization. Predicted to be located in cytoplasm; cytoskeleton; and membrane. Predicted to be active in sperm flagellum. Human ortholog(s) of this gene implicated in spermatogenic failure 42. Orthologous to human TTC29 (tetratricopeptide repeat domain 29). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 192.5) and Lung (RPKM 26.0) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ttc29 in Genome Data Viewer
    Location:
    19q11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (46436526..46654891, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (29531707..29750635, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (33205576..33424955, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L21-like Neighboring gene POU class 4 homeobox 2 Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene adaptor related protein complex 3 subunit sigma 1, pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cilium movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cilium movement ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cilium movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cilium organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cilium organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in sperm flagellum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in sperm flagellum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in sperm flagellum ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    tetratricopeptide repeat protein 29
    Names
    TPR repeat protein 29

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013890.1 → NP_001013912.1  tetratricopeptide repeat protein 29

      See identical proteins and their annotated locations for NP_001013912.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078968
      UniProtKB/Swiss-Prot
      Q6AYP3
      UniProtKB/TrEMBL
      A0A0G2K1C1
      Related
      ENSRNOP00000071781.1, ENSRNOT00000089569.3
      Conserved Domains (2) summary
      sd00006
      Location:275 → 302
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:311 → 386
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      46436526..46654891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017601216.3 → XP_017456705.1  tetratricopeptide repeat protein 29 isoform X2

      UniProtKB/Swiss-Prot
      Q6AYP3
      UniProtKB/TrEMBL
      A0A0G2K1C1
      Conserved Domains (2) summary
      sd00006
      Location:275 → 302
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:311 → 386
      TPR_12; Tetratricopeptide repeat

    2. XM_063277892.1 → XP_063133962.1  tetratricopeptide repeat protein 29 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K1C1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AYP3.1 GenPept UniProtKB/Swiss-Prot:Q6AYP3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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