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    Smok2a sperm motility kinase 2A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292316, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Smok2aprovided by RGD
    Official Full Name
    sperm motility kinase 2Aprovided by RGD
    Primary source
    RGD:1565233
    See related
    EnsemblRapid:ENSRNOG00000084922 AllianceGenome:RGD:1565233
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565233
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 184.1) and Uterus (RPKM 9.4) See more
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    Genomic context

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    See Smok2a in Genome Data Viewer
    Location:
    1q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (57703104..57716705)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (53570737..53580441)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (54851340..54854266, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene sperm motility kinase 2A like 2 Neighboring gene large ribosomal subunit protein eL24-like Neighboring gene BRCA1/BRCA2-containing complex, subunit 3, pseudogene 5 Neighboring gene sperm motility kinase 2A like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sperm motility kinase 2A
    NP_001178548.2
    XP_038959424.1
    XP_063138960.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191619.3 → NP_001178548.2  sperm motility kinase 2A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      M0RD88
      Related
      ENSRNOP00000111617.1, ENSRNOT00000122785.1
      Conserved Domains (2) summary
      cd14337
      Location:294 → 333
      UBA_MARK_Par1; UBA domain found in microtubule-associated protein (MAP)/microtubule affinity-regulating kinase (MARK)/ partitioning-defective 1 (Par-1) and similar proteins
      cd14003
      Location:26 → 274
      STKc_AMPK-like; Catalytic domain of AMP-activated protein kinase-like Serine/Threonine Kinases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      57703104..57716705
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039103496.2 → XP_038959424.1  sperm motility kinase 2A isoform X1

      Conserved Domains (2) summary
      cd14337
      Location:294 → 333
      UBA_MARK_Par1; UBA domain found in microtubule-associated protein (MAP)/microtubule affinity-regulating kinase (MARK)/ partitioning-defective 1 (Par-1) and similar proteins
      cd14003
      Location:26 → 274
      STKc_AMPK-like; Catalytic domain of AMP-activated protein kinase-like Serine/Threonine Kinases

    2. XM_063282890.1 → XP_063138960.1  sperm motility kinase 2A isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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