Ovol3 ovo-like zinc finger 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ovol3provided by RGD
Official Full Name: ovo-like zinc finger 3provided by RGD
Primary source: RGD:1583800
See related: EnsemblRapid:ENSRNOG00000062751 AllianceGenome:RGD:1583800
Gene type: protein coding
RefSeq status: INFERRED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in epidermal cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human OVOL3 (ovo like zinc finger 3). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Note: GeneIDs 100912425 and 365226 are annotated independently on Rnor_6.0 (Annotation Release 105) but may be redundant loci. [24 Feb 2015]
Expression: Biased expression in Testes (RPKM 3.5), Lung (RPKM 2.5) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 1q21

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (94612417..94616053, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (85484956..85488592, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (91037531..91041167)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in epidermal cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: putative transcription factor ovo-like protein 3

Names: OVO homolog-like 3; ovo-like 3; putative transcription factor ovo-like protein 3-like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001289820.2 → NP_001276749.1 putative transcription factor ovo-like protein 3

See identical proteins and their annotated locations for NP_001276749.1

Status: INFERRED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

D3ZKH1

Related

ENSRNOP00000091349.1, ENSRNOT00000103780.2

Conserved Domains (4) summary

COG5048
Location:19 → 127

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:71 → 91

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:97 → 119

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:111 → 136

zf-H2C2_2; Zinc-finger double domain