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    Lipm lipase, family member M [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309528, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lipmprovided by RGD
    Official Full Name
    lipase, family member Mprovided by RGD
    Primary source
    RGD:1304912
    See related
    EnsemblRapid:ENSRNOG00000019301 AllianceGenome:RGD:1304912
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lipl3
    Summary
    Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in lipid catabolic process. Orthologous to human LIPM (lipase family member M). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 10.0), Uterus (RPKM 4.5) and 3 other tissues See more
    Orthologs
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    Genomic context

    See Lipm in Genome Data Viewer
    Location:
    1q52
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (241031382..241050796)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (231618145..231637599)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (252409232..252428567)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene lipase, family member K Neighboring gene lipase, family member N Neighboring gene ankyrin repeat domain 22 Neighboring gene STAM binding protein-like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    lipase member M
    Names
    lipase-like, ab-hydrolase domain containing 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432293.1NP_001419222.1  lipase member M precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      D4AA61

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      241031382..241050796
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_220066.9XP_220066.4  lipase member M

      Related
      ENSRNOP00000026219.3, ENSRNOT00000026219.7
      Conserved Domains (3) summary
      pfam00561
      Location:92392
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam04083
      Location:49111
      Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
      pfam12695
      Location:93231
      Abhydrolase_5; Alpha/beta hydrolase family