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    Igsf6 immunoglobulin superfamily, member 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171064, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Igsf6provided by RGD
    Official Full Name
    immunoglobulin superfamily, member 6provided by RGD
    Primary source
    RGD:620663
    See related
    EnsemblRapid:ENSRNOG00000017277 AllianceGenome:RGD:620663
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    DORA
    Summary
    Predicted to be located in membrane. Orthologous to human IGSF6 (immunoglobulin superfamily member 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 135.8), Lung (RPKM 107.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Igsf6 in Genome Data Viewer
    Location:
    1q36
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (185041462..185051956, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (175610167..175620662, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (190997029..191007503, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene major facilitator superfamily domain containing 13B Neighboring gene U6 spliceosomal RNA Neighboring gene methyltransferase 9, His-X-His N1(pi)-histidine Neighboring gene otoancorin Neighboring gene uncharacterized LOC108349630

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. CD40L activation of dendritic cells down-regulates DORA, a novel member of the immunoglobulin superfamily. Bates EE, et al. Mol Immunol, 1998 Jun. PMID 9809579

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    immunoglobulin superfamily member 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133542.3 → NP_598226.2  immunoglobulin superfamily member 6 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      Q9Z0K5
      UniProtKB/TrEMBL
      A6I8U1
      Related
      ENSRNOP00000023262.3, ENSRNOT00000023262.4
      Conserved Domains (2) summary
      cd00096
      Location:45 → 54
      Ig; Ig strand B [structural motif]
      cl11960
      Location:34 → 142
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      185041462..185051956 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Z0K5.1 GenPept UniProtKB/Swiss-Prot:Q9Z0K5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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