U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Fam115e family with sequence similarity 115, member E [ Rattus norvegicus (Norway rat) ]

    Gene ID: 494321, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fam115eprovided by RGD
    Official Full Name
    family with sequence similarity 115, member Eprovided by RGD
    Primary source
    RGD:1359405
    See related
    EnsemblRapid:ENSRNOG00000038872 AllianceGenome:RGD:1359405
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Eapa2; Tcaf3
    Summary
    Predicted to enable transmembrane transporter binding activity. Predicted to be active in plasma membrane. Orthologous to human TCAF2 (TRPM8 channel associated factor 2) and TCAF2C (TRPM8 channel associated factor 2C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 2.2), Adrenal (RPKM 2.1) and 9 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Fam115e in Genome Data Viewer
    Location:
    4q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (72476904..72491208, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (71510278..71524582, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (72010583..72023952, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily R member 3B Neighboring gene olfactory receptor family 10 subfamily AC member 1 Neighboring gene TRPM8 channel associated factor 2C Neighboring gene TRPM8 channel-associated factor 2-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC72615

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transmembrane transporter binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    TRPM8 channel-associated factor 3
    Names
    experimental autoimmune prostatitis antigen 2 homolog
    protein FAM115E

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009534.1NP_001009534.1  TRPM8 channel-associated factor 3

      See identical proteins and their annotated locations for NP_001009534.1

      Status: PROVISIONAL

      Source sequence(s)
      BC061995
      UniProtKB/Swiss-Prot
      Q6P6V7
      UniProtKB/TrEMBL
      A6IF82, D3ZRI3
      Related
      ENSRNOP00000056152.3, ENSRNOT00000059395.5
      Conserved Domains (1) summary
      pfam13402
      Location:520880
      Peptidase_M60; Peptidase M60, enhancin and enhancin-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      72476904..72491208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)