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    Tmed8 transmembrane p24 trafficking protein 8 [ Mus musculus (house mouse) ]

    Gene ID: 382620, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmed8provided by MGI
    Official Full Name
    transmembrane p24 trafficking protein 8provided by MGI
    Primary source
    MGI:MGI:1923480
    See related
    Ensembl:ENSMUSG00000034111 AllianceGenome:MGI:1923480
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mem1; Gm1184; 6430595O10Rik
    Summary
    Is expressed in early conceptus. Orthologous to human TMED8 (transmembrane p24 trafficking protein family member 8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 9.6), frontal lobe adult (RPKM 5.6) and 26 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tmed8 in Genome Data Viewer
    Location:
    12 D2; 12 41.36 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (87195547..87247264, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (87166242..87200457, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene neuroglobin Neighboring gene protein-O-mannosyltransferase 2 Neighboring gene STARR-positive B cell enhancer ABC_E10770 Neighboring gene STARR-positive B cell enhancer ABC_E10771 Neighboring gene glutathione transferase zeta 1 (maleylacetoacetate isomerase) Neighboring gene predicted gene 6566 Neighboring gene STARR-positive B cell enhancer ABC_E9041 Neighboring gene sterile alpha motif domain containing 15 Neighboring gene NADP+ dependent oxidoreductase domain containing 1 Neighboring gene VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog Neighboring gene AHA1, activator of heat shock protein ATPase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    protein TMED8
    Names
    maternal embryonic message 1
    transmembrane emp24 domain containing 8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033475.3NP_001028647.1  protein TMED8

      See identical proteins and their annotated locations for NP_001028647.1

      Status: PROVISIONAL

      Source sequence(s)
      AC132609
      Consensus CDS
      CCDS26072.1
      UniProtKB/Swiss-Prot
      Q3UHI4
      UniProtKB/TrEMBL
      B9EKE7
      Related
      ENSMUSP00000043742.6, ENSMUST00000037418.7
      Conserved Domains (1) summary
      pfam13897
      Location:186325
      GOLD_2; Golgi-dynamics membrane-trafficking

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      87195547..87247264 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157514.1XP_036013407.1  protein TMED8 isoform X1

      Conserved Domains (1) summary
      pfam13897
      Location:281331
      GOLD_2; Golgi-dynamics membrane-trafficking
    2. XM_030246805.2XP_030102665.1  protein TMED8 isoform X3

      Conserved Domains (1) summary
      pfam13897
      Location:76215
      GOLD_2; Golgi-dynamics membrane-trafficking
    3. XM_006516050.5XP_006516113.1  protein TMED8 isoform X2

      Conserved Domains (1) summary
      pfam13897
      Location:117256
      GOLD_2; Golgi-dynamics membrane-trafficking