U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cdo-1 Cysteine dioxygenase 1 [ Caenorhabditis elegans ]

    Gene ID: 180434, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cdo-1
    Official Full Name
    Cysteine dioxygenase 1
    Primary source
    WormBase:WBGene00018986
    Locus tag
    CELE_F56F10.3
    See related
    AllianceGenome:WB:WBGene00018986
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cysteine dioxygenase activity and ferrous iron binding activity. Predicted to be involved in L-cysteine catabolic process. Is expressed in hypodermis; intestine; and tail. Orthologous to human CDO1 (cysteine dioxygenase type 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cdo-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (862267..863578, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F-box domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Lethal giant larvae homologue 2 domain-containing protein Neighboring gene tRNA-Tyr Neighboring gene Putative serine protease F56F10.1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans. Warnhoff K, et al. Elife, 2024 Feb 13. PMID 38349720, Free PMC Article
    2. Structure activity relationship and target prediction for ABX464 analogues in Caenorhabditis elegans. Shanley HT, et al. Bioorg Med Chem, 2024 Jan 15. PMID 38134663
    3. Molybdenum cofactor transfer from bacteria to nematode mediates sulfite detoxification. Warnhoff K, et al. Nat Chem Biol, 2019 May. PMID 30911177, Free PMC Article
    4. Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy. Ellwood RA, et al. Commun Biol, 2022 Nov 16. PMID 36385509, Free PMC Article
    5. Gene CATCHR--gene cloning and tagging for Caenorhabditis elegans using yeast homologous recombination: a novel approach for the analysis of gene expression. Sassi HE, et al. Nucleic Acids Res, 2005 Oct 27. PMID 16254074, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cysteine dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cysteine dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ferrous iron binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-cysteine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in taurine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Cysteine dioxygenase 1
    NP_508168.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      862267..863578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075767.7 → NP_508168.1  Cysteine dioxygenase 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508168.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20893
      Conserved Domains (1) summary
      pfam05995
      Location:3 → 162
      CDO_I; Cysteine dioxygenase type I
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q20893.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous