clec-196 C-type lectin domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: clec-196
Official Full Name: C-type lectin domain-containing protein
Primary source: WormBase:WBGene00009156
Locus tag: CELE_F26D10.12
See related: AllianceGenome:WB:WBGene00009156
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Orthologous to several human genes including CLEC7A (C-type lectin domain containing 7A). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See clec-196 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 3

Sequence:: Chromosome: IV; NC_003282.8 (17276956..17277748)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

F26D10.11 (e-PCR)
- UniSTS:316634

F26D10.12 (e-PCR)
- UniSTS:316635

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables carbohydrate binding	IBA Inferred from Biological aspect of Ancestor more info
enables pattern recognition receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: C-type lectin domain-containing protein

NP_001255932.1

Confirmed by transcript evidence

NP_001255933.1

Confirmed by transcript evidence

NP_001299955.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

17276956..17277748

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001269003.2 → NP_001255932.1 C-type lectin domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001255932.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9XVT9

Conserved Domains (1) summary

smart00034
Location:29 → 142

CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
NM_001313026.3 → NP_001299955.1 C-type lectin domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3ARI7
NM_001269004.3 → NP_001255933.1 C-type lectin domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001255933.1

Status: REVIEWED

UniProtKB/TrEMBL

F5GUE2