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    arf-1 ADP-ribosylation factor 1-like 2 [ Caenorhabditis elegans ]

    Gene ID: 175801, updated on 27-Dec-2024

    Summary

    Official Symbol
    arf-1
    Official Full Name
    ADP-ribosylation factor 1-like 2
    Primary source
    WormBase:WBGene00000182
    Locus tag
    CELE_B0336.2
    See related
    AllianceGenome:WB:WBGene00000182
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTP binding activity. Involved in several processes, including oocyte development; regulation of apoptotic process involved in development; and regulation of receptor-mediated endocytosis. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary muscle; hypodermis; nervous system; reproductive system; and vulval precursor cell. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ARF GTPase 1) and ARF3 (ARF GTPase 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See arf-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (5716115..5717544)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene C3H1-type domain-containing protein;RRM domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding  
    enables GTP binding  
    enables GTPase activity  
    enables hydrolase activity  
    Component Evidence Code Pubs
    located_in Golgi apparatus  
    located_in Golgi membrane  
    is_active_in cytoplasm  
    located_in endoplasmic reticulum PubMed 
    located_in membrane  
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    ADP-ribosylation factor 1-like 2
    NP_001367325.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      5716115..5717544
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001379728.2NP_001367325.1  ADP-ribosylation factor 1-like 2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q10943
      Conserved Domains (1) summary
      cl38936
      Location:5179
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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