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    rfip-1 FIP-RBD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173998, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rfip-1
    Official Full Name
    FIP-RBD domain-containing protein
    Primary source
    WormBase:WBGene00018869
    Locus tag
    CELE_F55C12.1
    See related
    AllianceGenome:WB:WBGene00018869
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in endocytic recycling and regulation of cytokinesis. Predicted to be located in endosome and membrane. Predicted to be active in cleavage furrow; cytoplasmic vesicle; and midbody. Is expressed in several structures, including excretory canal; head neurons; intestine; pharynx; and tail neurons. Orthologous to human RAB11FIP3 (RAB11 family interacting protein 3) and RAB11FIP4 (RAB11 family interacting protein 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rfip-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (5884552..5892227)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene LisH domain-containing protein;VQ domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hox Genes Promote Neuronal Subtype Diversification through Posterior Induction in Caenorhabditis elegans. Zheng C, et al. Neuron, 2015 Nov 4. PMID 26539892, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endocytic recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cleavage furrow IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endocytic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in recycling endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in recycling endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    FIP-RBD domain-containing protein
    NP_001367895.1
    • Confirmed by transcript evidence
    NP_001367896.1
    • Confirmed by transcript evidence
    NP_495175.1
    • Confirmed by transcript evidence
    NP_872036.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5884552..5892227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381439.3 → NP_001367895.1  FIP-RBD domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20813
      Conserved Domains (2) summary
      COG1196
      Location:43 → 265
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam09457
      Location:294 → 330
      RBD-FIP; FIP domain

    2. NM_001381438.1 → NP_001367896.1  FIP-RBD domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IG15
      Conserved Domains (2) summary
      COG1196
      Location:57 → 279
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam09457
      Location:308 → 344
      RBD-FIP; FIP domain

    3. NM_182236.5 → NP_872036.1  FIP-RBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_872036.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IG14
      Conserved Domains (2) summary
      COG1196
      Location:8 → 237
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam09457
      Location:256 → 292
      RBD-FIP; FIP domain

    4. NM_062774.5 → NP_495175.1  FIP-RBD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495175.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95ZS6
      Conserved Domains (2) summary
      COG1196
      Location:60 → 282
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam09457
      Location:311 → 347
      RBD-FIP; FIP domain

    RNA

    1. NR_151563.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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