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    cdh-8 Cadherin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 184652, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cdh-8
    Official Full Name
    Cadherin domain-containing protein
    Primary source
    WormBase:WBGene00017576
    Locus tag
    CELE_F18F11.3
    See related
    AllianceGenome:WB:WBGene00017576
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cdh-8 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    26
    Sequence:
    Chromosome: IV; NC_003282.8 (339808..359293)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Glycosyltransferase family 92 protein Neighboring gene Peroxisomal membrane protein 4 Neighboring gene ncRNA Neighboring gene Calponin-homology (CH) domain-containing protein;FiLamiN (actin binding protein) homolog Neighboring gene ncRNA Neighboring gene Sphingosine-1-phosphate lyase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In situ structure of intestinal apical surface reveals nanobristles on microvilli. Zhu H, et al. Proc Natl Acad Sci U S A, 2022 Jun 14. PMID 35666862, Free PMC Article
    2. Nematode-specific cadherin CDH-8 acts as a receptor for Cry5B toxin in Caenorhabditis elegans. Peng D, et al. Appl Microbiol Biotechnol, 2018 Apr. PMID 29502179
    3. Use of RNAi as a preliminary tool for screening putative receptors of nematicidal toxins from Bacillus thuringiensis. García-Montelongo M, et al. Arch Microbiol, 2021 May. PMID 33432376
    4. The cadherin superfamily. Pettitt J. WormBook, 2005 Dec 29. PMID 18050421, Free PMC Article
    5. Cell adhesion receptors in C. elegans. Cox EA, et al. J Cell Sci, 2004 Apr 15. PMID 15090591

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cadherin domain-containing protein
    NP_001294359.1
    • Confirmed by transcript evidence
    NP_001294409.1
    • Partially confirmed by transcript evidence
    NP_001294410.1
    • Partially confirmed by transcript evidence
    NP_001294411.1
    • Partially confirmed by transcript evidence
    NP_001294412.1
    • Partially confirmed by transcript evidence
    NP_001294413.1
    • Partially confirmed by transcript evidence
    NP_001294414.1
    • Partially confirmed by transcript evidence
    NP_001294415.1
    • Partially confirmed by transcript evidence
    NP_001294416.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      339808..359293
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001307480.3 → NP_001294409.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294409.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PEK5
      Conserved Domains (1) summary
      cd11304
      Location:552 → 647
      Cadherin_repeat; Cadherin tandem repeat domain

    2. NM_001307483.3 → NP_001294412.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294412.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PM66
      Conserved Domains (1) summary
      cd11304
      Location:552 → 647
      Cadherin_repeat; Cadherin tandem repeat domain

    3. NM_001307487.3 → NP_001294416.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294416.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PBR4
      Conserved Domains (1) summary
      cd11304
      Location:552 → 647
      Cadherin_repeat; Cadherin tandem repeat domain

    4. NM_001307484.3 → NP_001294413.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294413.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PRG1
      Conserved Domains (1) summary
      cd11304
      Location:552 → 647
      Cadherin_repeat; Cadherin tandem repeat domain

    5. NM_001307482.3 → NP_001294411.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294411.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PBR0
      Conserved Domains (1) summary
      cd11304
      Location:552 → 647
      Cadherin_repeat; Cadherin tandem repeat domain

    6. NM_001307486.4 → NP_001294415.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294415.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PBD6
      Conserved Domains (1) summary
      cd11304
      Location:552 → 647
      Cadherin_repeat; Cadherin tandem repeat domain

    7. NM_001307481.3 → NP_001294410.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294410.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PBD1
      Conserved Domains (1) summary
      cd11304
      Location:552 → 647
      Cadherin_repeat; Cadherin tandem repeat domain

    8. NM_001307485.3 → NP_001294414.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294414.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PEL1
      Conserved Domains (1) summary
      cd11304
      Location:552 → 647
      Cadherin_repeat; Cadherin tandem repeat domain

    9. NM_001307430.3 → NP_001294359.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294359.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PBI3
    Nucleotide Protein
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