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    clec-53 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171967, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clec-53
    Official Full Name
    C-type lectin domain-containing protein
    Primary source
    WormBase:WBGene00020191
    Locus tag
    CELE_T03F1.10
    See related
    AllianceGenome:WB:WBGene00020191
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable signaling receptor activity. Is expressed in intestine. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human REG1A (regenerating family member 1 alpha). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clec-53 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (3871474..3873402, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ubiquinone biosynthesis protein coq-4, mitochondrial Neighboring gene ncRNA Neighboring gene Ubiquitin-like modifier-activating enzyme 5 Neighboring gene Protein SYS1 homolog Neighboring gene Pre-mRNA-splicing factor SYF1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in Caenorhabditis elegans. Hammerquist AM, et al. Sci Rep, 2020 Nov 9. PMID 33168938, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C-type lectin domain-containing protein
    NP_491247.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3871474..3873402 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058846.6 → NP_491247.2  C-type lectin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491247.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91429
      Conserved Domains (2) summary
      cd00037
      Location:32 → 147
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      smart00034
      Location:166 → 303
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    Nucleotide Protein
    Heading Accession and Version

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