U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    clec-52 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181855, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    clec-52
    Official Full Name
    C-type lectin domain-containing protein
    Primary source
    WormBase:WBGene00015052
    Locus tag
    CELE_B0218.8
    See related
    AllianceGenome:WB:WBGene00015052
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable signaling receptor activity. Involved in defense response to Gram-positive bacterium. Is expressed in intestine; nervous system; and pharynx. Orthologous to several human genes including LY75-CD302 (LY75-CD302 readthrough); LY75 (lymphocyte antigen 75); and MRC2 (mannose receptor C-type 2). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See clec-52 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (8167164..8168760, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Fatty acid amide hydrolase 1 Neighboring gene C-type lectin domain-containing protein Neighboring gene Ovule protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Early-life exposure to mycotoxin zearalenone exacerbates aberrant immune response, oxidative stress, and mortality of Caenorhabditis elegans under pathogen Bacillus thuringiensis infection. How CM, et al. Ecotoxicol Environ Saf, 2024 Mar 1. PMID 38342010
    2. Caenorhabditis elegans mounts a p38 MAPK pathway-mediated defence to Cutibacterium acnes infection. Huang X, et al. Cell Microbiol, 2020 Oct. PMID 32543022
    3. Chromosomal clustering and GATA transcriptional regulation of intestine-expressed genes in C. elegans. Pauli F, et al. Development, 2006 Jan. PMID 16354718, Free PMC Article
    4. Determining Toxic Potencies of Water-Soluble Contaminants in Wastewater Influents and Effluent Using Gene Expression Profiling in C. elegans as a Bioanalytical Tool. Karengera A, et al. Arch Environ Contam Toxicol, 2022 Oct. PMID 36190544, Free PMC Article
    5. Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes. Visvikis O, et al. Immunity, 2014 Jun 19. PMID 24882217, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-positive bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    C-type lectin domain-containing protein
    NP_501371.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8167164..8168760 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068970.7 → NP_501371.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501371.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17452
      Conserved Domains (2) summary
      cd00037
      Location:32 → 147
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      smart00034
      Location:166 → 303
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous