U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cdh-12 Cadherin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190583, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cdh-12
    Official Full Name
    Cadherin domain-containing protein
    Primary source
    WormBase:WBGene00022103
    Locus tag
    CELE_Y71D11A.1
    See related
    AllianceGenome:WB:WBGene00022103
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cdh-12 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    26
    Sequence:
    Chromosome: III; NC_003281.10 (1152044..1181147)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase Neighboring gene putative ligand-gated ion channel 46 Neighboring gene ncRNA Neighboring gene Tudor domain-containing protein Neighboring gene ncRNA Neighboring gene tRNA-Ile Neighboring gene ncRNA Neighboring gene tRNA-Ile Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Enhancer of AKt-1 null Neighboring gene Tr-type G domain-containing protein Neighboring gene DUF19 domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The cadherin superfamily. Pettitt J. WormBook, 2005 Dec 29. PMID 18050421, Free PMC Article
    2. Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity. Zhang Y, et al. Dev Biol, 2008 Mar 15. PMID 18241854, Free PMC Article
    3. Function of cell adhesion molecules in differentiation of ray sensory neurons in C. elegans. Sakai N, et al. G3 (Bethesda), 2023 Mar 9. PMID 36573343, Free PMC Article
    4. EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity. Alam H, et al. Cell Metab, 2010 Jul 7. PMID 20620993, Free PMC Article
    5. Cell adhesion receptors in C. elegans. Cox EA, et al. J Cell Sci, 2004 Apr 15. PMID 15090591

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Cadherin domain-containing protein
    NP_001360600.1
    • Confirmed by transcript evidence
    NP_001360601.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1152044..1181147
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373846.2 → NP_001360600.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V6M3X3
      Conserved Domains (2) summary
      cd11304
      Location:1054 → 1142
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam15662
      Location:2056 → 2139
      SPATA3; Spermatogenesis-associated protein 3 family

    2. NM_001373847.2 → NP_001360601.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IJU8
      Conserved Domains (2) summary
      cd11304
      Location:153 → 241
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam15662
      Location:1155 → 1238
      SPATA3; Spermatogenesis-associated protein 3 family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools