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    tmem-208 Transmembrane protein 208 [ Caenorhabditis elegans ]

    Gene ID: 172649, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tmem-208
    Official Full Name
    Transmembrane protein 208
    Primary source
    WormBase:WBGene00011033
    Locus tag
    CELE_R05D11.5
    See related
    AllianceGenome:WB:WBGene00011033
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in vacuolar protein processing. Predicted to be located in endoplasmic reticulum membrane and vacuole. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human TMEM208 (transmembrane protein 208). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tmem-208 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (8592092..8592928)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Smad protein daf-8 Neighboring gene putative nuclear transport factor 2 Neighboring gene Sphingomyelin phosphodiesterase 4 Neighboring gene Partner of xrn-2 protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RNA polymerase II C-terminal domain phosphorylation patterns in Caenorhabditis elegans operons, polycistronic gene clusters with only one promoter. Garrido-Lecca A, et al. Mol Cell Biol, 2010 Aug. PMID 20498277, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in vacuolar protein processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane protein 208
    NP_492323.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8592092..8592928
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059922.7 → NP_492323.1  Transmembrane protein 208 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492323.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21737
      Conserved Domains (1) summary
      pfam05620
      Location:5 → 163
      DUF788; Protein of unknown function (DUF788)
    Nucleotide Protein
    Heading Accession and Version

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