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    F49E10.2 Carotenoid oxygenase [ Caenorhabditis elegans ]

    Gene ID: 180855, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F49E10.2
    Official Full Name
    Carotenoid oxygenase
    Primary source
    WormBase:WBGene00018640
    Locus tag
    CELE_F49E10.2
    See related
    AllianceGenome:WB:WBGene00018640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable beta-carotene 15,15'-dioxygenase activity and carotenoid dioxygenase activity. Predicted to be involved in carotene catabolic process and retinal metabolic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F49E10.2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (5890380..5894757)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Rab-GAP TBC domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables beta-carotene 15,15'-dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables carotenoid dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carotene catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retinal metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Carotenoid oxygenase
    NP_508986.1
    • Confirmed by transcript evidence
    NP_508987.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5890380..5894757
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076585.4 → NP_508986.1  Carotenoid oxygenase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508986.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L060
      Conserved Domains (1) summary
      cl10080
      Location:46 → 546
      RPE65; Retinal pigment epithelial membrane protein

    2. NM_076586.5 → NP_508987.1  Carotenoid oxygenase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508987.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20599
      Conserved Domains (1) summary
      cl10080
      Location:46 → 546
      RPE65; Retinal pigment epithelial membrane protein
    Nucleotide Protein
    Heading Accession and Version

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