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    nhr-10 Nuclear hormone receptor family member nhr-10 [ Caenorhabditis elegans ]

    Gene ID: 175993, updated on 9-Dec-2024

    Summary

    Official Symbol
    nhr-10
    Official Full Name
    Nuclear hormone receptor family member nhr-10
    Primary source
    WormBase:WBGene00003609
    Locus tag
    CELE_B0280.8
    See related
    AllianceGenome:WB:WBGene00003609
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Located in chromatin. Is expressed in head and intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See nhr-10 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (7112295..7115438, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein odd-skipped-related 1 Neighboring gene Uncharacterized protein Neighboring gene U3 small nucleolar RNA-associated protein 18 homolog Neighboring gene Probable-ribose 5-phosphate isomerase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclear receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of propionate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromatin IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Nuclear hormone receptor family member nhr-10
    NP_498554.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7112295..7115438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066153.7NP_498554.1  Nuclear hormone receptor family member nhr-10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498554.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41999
      UniProtKB/TrEMBL
      Q86PK9
      Conserved Domains (2) summary
      cd06960
      Location:1893
      NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
      smart00430
      Location:200359
      HOLI; Ligand binding domain of hormone receptors