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    T04B8.5 AA_permease domain-containing protein;Solute carrier family 12 member 9 [ Caenorhabditis elegans ]

    Gene ID: 173453, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T04B8.5
    Official Full Name
    AA_permease domain-containing protein;Solute carrier family 12 member 9
    Primary source
    WormBase:WBGene00020207
    Locus tag
    CELE_T04B8.5
    See related
    AllianceGenome:WB:WBGene00020207
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable potassium:chloride symporter activity. Predicted to be involved in several processes, including chloride ion homeostasis; chloride transmembrane transport; and potassium ion homeostasis. Predicted to be located in membrane. Is expressed in body wall musculature; excretory cell; nervous system; and pharynx. Orthologous to human SLC12A9 (solute carrier family 12 member 9). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T04B8.5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    14
    Sequence:
    Chromosome: II; NC_003280.10 (614770..624543, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene C-type lectin domain-containing protein Neighboring gene pseudo Neighboring gene Arrestin C-terminal-like domain-containing protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chloride:monoatomic cation symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium:chloride symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell volume homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chloride ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chloride transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    AA_permease domain-containing protein;Solute carrier family 12 member 9
    NP_001022305.1
    • Confirmed by transcript evidence
    NP_001022306.1
    • Confirmed by transcript evidence
    NP_001300592.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      614770..624543 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027134.6 → NP_001022305.1  AA_permease domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022305.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44846
      Conserved Domains (2) summary
      TIGR00930
      Location:85 → 943
      2a30; K-Cl cotransporter
      pfam03522
      Location:593 → 943
      SLC12; Solute carrier family 12

    2. NM_001027135.3 → NP_001022306.1  Solute carrier family 12 member 9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022306.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6A583
      Conserved Domains (2) summary
      TIGR00930
      Location:72 → 930
      2a30; K-Cl cotransporter
      pfam03522
      Location:580 → 930
      SLC12; Solute carrier family 12

    3. NM_001313663.3 → NP_001300592.1  Solute carrier family 12 member 9 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AX20
      Conserved Domains (2) summary
      TIGR00930
      Location:13 → 871
      2a30; K-Cl cotransporter
      pfam03522
      Location:521 → 871
      SLC12; Solute carrier family 12

    RNA

    1. NR_132579.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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