U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    nlp-2 Neuropeptide-Like Protein [ Caenorhabditis elegans ]

    Gene ID: 188857, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    nlp-2
    Official Full Name
    Neuropeptide-Like Protein
    Primary source
    WormBase:WBGene00003740
    Locus tag
    CELE_T24D8.5
    See related
    AllianceGenome:WB:WBGene00003740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in embryo development and positive regulation of error-prone translesion synthesis. Is expressed in head neurons; intestine; and uv1. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See nlp-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    3
    Sequence:
    Chromosome: X; NC_003284.9 (2343947..2344766, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Neuropeptide-Like Protein Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. New alleles of nlp-2 , nlp-22 , and nlp-23 demonstrate that they are dispensable for stress-induced sleep in C. elegans. Aviles S, et al. MicroPubl Biol, 2024. PMID 38371321, Free PMC Article
    2. EGL-38/Pax coordinates development in the Caenhorhabditis elegans egg-laying system through EGF pathway dependent and independent functions. Webb Chasser AM, et al. Mech Dev, 2019 Oct. PMID 31398431, Free PMC Article
    3. RPamide neuropeptides NLP-22 and NLP-2 act through GnRH-like receptors to promote sleep and wakefulness in C. elegans. Van der Auwera P, et al. Sci Rep, 2020 Jun 18. PMID 32555288, Free PMC Article
    4. The actions of Caenorhabditis elegans neuropeptide-like peptides (NLPs) on body wall muscle of Ascaris suum and pharyngeal muscle of C. elegans. Papaioannou S, et al. Acta Biol Hung, 2008. PMID 18652392
    5. A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis. Roerink SF, et al. PLoS Genet, 2012 Jun. PMID 22761594, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in embryo development ending in birth or egg hatching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of error-prone translesion synthesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of error-prone translesion synthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Neuropeptide-Like Protein
    NP_508426.1
    • Product from WormBase gene class nlp;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      2343947..2344766 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076025.9 → NP_508426.1  Neuropeptide-Like Protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508426.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22739
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools