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    col-33 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177191, updated on 9-Dec-2024

    Summary

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    Official Symbol
    col-33
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00000610
    Locus tag
    CELE_F36A4.6
    See related
    AllianceGenome:WB:WBGene00000610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human COL21A1 (collagen type XXI alpha 1 chain). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See col-33 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (4263293..4265223)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase II subunit RPB1 Neighboring gene ncRNA Neighboring gene MBL fold metallo-hydrolase Neighboring gene TransThyretin-Related family domain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. dpy-13: a nematode collagen gene that affects body shape. von Mende N, et al. Cell, 1988 Nov 18. PMID 2846184
    2. Regulation of tissue-specific and extracellular matrix-related genes by a class I histone deacetylase. Whetstine JR, et al. Mol Cell, 2005 May 13. PMID 15893731
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_500524.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      4263293..4265223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068123.5 → NP_500524.2  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500524.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20091
      Conserved Domains (1) summary
      smart01088
      Location:15 → 67
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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