ser-3 G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Official Symbol: ser-3
Official Full Name: G-protein coupled receptors family 1 profile domain-containing protein
Primary source: WormBase:WBGene00004778
Locus tag: CELE_K02F2.6
See related: AllianceGenome:WB:WBGene00004778
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables octopamine receptor activity. Involved in octopamine or tyramine signaling pathway. Predicted to be located in membrane and synapse. Predicted to be active in dendrite and plasma membrane. Is expressed in several structures, including head muscle; hermaphrodite gonad; nervous system; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

The results show that the endogenous octopamine system, ser-3, in C. elegans, is activated by starvation.
Title: Starvation induces cAMP response element-binding protein-dependent gene expression through octopamine-Gq signaling in Caenorhabditis elegans.

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Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables neurotransmitter receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables octopamine receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables octopamine receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables signaling receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled serotonin receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in chemical synaptic transmission	IBA Inferred from Biological aspect of Ancestor more info
involved_in octopamine or tyramine signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in response to stimulus	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in dendrite	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IC Inferred by Curator more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info

Preferred Names: G-protein coupled receptors family 1 profile domain-containing protein

NP_491954.1

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The following sections contain reference sequences that belong to a specific genome build. Explain