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    egl-23 Potassium channel domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178358, updated on 9-Dec-2024

    Summary

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    Official Symbol
    egl-23
    Official Full Name
    Potassium channel domain-containing protein
    Primary source
    WormBase:WBGene00001190
    Locus tag
    CELE_Y37A1B.11
    See related
    AllianceGenome:WB:WBGene00001190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See egl-23 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    14
    Sequence:
    Chromosome: IV; NC_003282.8 (13989081..14012074)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Ala

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A sleep-active neuron can promote survival while sleep behavior is disturbed. Busack I, et al. PLoS Genet, 2023 Mar. PMID 36917595, Free PMC Article
    2. Reversal of a muscle response to GABA during C. elegans male development. Reiner DJ, et al. J Neurosci, 1995 Sep. PMID 7666193, Free PMC Article
    3. Potassium channels in C. elegans. Salkoff L, et al. WormBook, 2005 Dec 30. PMID 18050399, Free PMC Article
    4. Characterization of a germ-line proliferation mutation in C. elegans. Beanan MJ, et al. Development, 1992 Nov. PMID 1289064
    5. Analysis of dominant mutations affecting muscle excitation in Caenorhabditis elegans. Reiner DJ, et al. Genetics, 1995 Nov. PMID 8582640, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables outward rectifier potassium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium ion leak channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Potassium channel domain-containing protein
    NP_001255775.1
    • Confirmed by transcript evidence
    NP_001255776.1
    • Confirmed by transcript evidence
    NP_001293999.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13989081..14012074
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268846.3 → NP_001255775.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255775.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z3L1
      Conserved Domains (1) summary
      pfam07885
      Location:217 → 275
      Ion_trans_2; Ion channel

    2. NM_001307070.3 → NP_001293999.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293999.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AL62
      Conserved Domains (2) summary
      pfam07885
      Location:174 → 234
      Ion_trans_2; Ion channel
      pfam09404
      Location:84 → 185
      DUF2003; Eukaryotic protein of unknown function (DUF2003)

    3. NM_001268847.4 → NP_001255776.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255776.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXF6
      Conserved Domains (1) summary
      pfam07885
      Location:181 → 241
      Ion_trans_2; Ion channel
    Nucleotide Protein
    Heading Accession and Version

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