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    nkat-1 kynurenine--oxoglutarate transaminase [ Caenorhabditis elegans ]

    Gene ID: 185086, updated on 4-Jan-2025

    Summary

    Official Symbol
    nkat-1
    Official Full Name
    kynurenine--oxoglutarate transaminase
    Primary source
    WormBase:WBGene00009232
    Locus tag
    CELE_F28H6.3
    See related
    AllianceGenome:WB:WBGene00009232
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable kynurenine-oxoglutarate transaminase activity. Predicted to be involved in L-kynurenine metabolic process and biosynthetic process. Predicted to be active in mitochondrion. Is expressed in RID; RMDVL; and RMDVR. Orthologous to several human genes including KYAT1 (kynurenine aminotransferase 1). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See nkat-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (14137810..14140140, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene tRNA-His Neighboring gene tRNA-His Neighboring gene Homeodomain-only protein Neighboring gene Serine/threonine-protein kinase akt-2

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables kynurenine-oxoglutarate transaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in L-kynurenine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    kynurenine--oxoglutarate transaminase
    NP_510355.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14137810..14140140 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077954.4NP_510355.1  kynurenine--oxoglutarate transaminase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510355.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XX97
      Conserved Domains (1) summary
      COG0436
      Location:21425
      AspB; Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]