B0228.7 S-methyl-5'-thioadenosine phosphorylase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: B0228.7
Official Full Name: S-methyl-5'-thioadenosine phosphorylase
Primary source: WormBase:WBGene00015064
Locus tag: CELE_B0228.7
See related: AllianceGenome:WB:WBGene00015064
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable S-methyl-5-thioadenosine phosphorylase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Is expressed in Ea; Ep; intestine; and nervous system. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm and diaphyseal medullary stenosis with malignant fibrous histiocytoma. Orthologous to human MTAP (methylthioadenosine phosphorylase). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables S-methyl-5-thioadenosine phosphorylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables S-methyl-5-thioadenosine phosphorylase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-methionine salvage from methylthioadenosine	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-methionine salvage from methylthioadenosine	IEA Inferred from Electronic Annotation more info
involved_in nucleoside metabolic process	IEA Inferred from Electronic Annotation more info
involved_in purine ribonucleoside salvage	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_001367321.1

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