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    kxd-1 KxDL domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182578, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kxd-1
    Official Full Name
    KxDL domain-containing protein
    Primary source
    WormBase:WBGene00015742
    Locus tag
    CELE_C13F10.2
    See related
    AllianceGenome:WB:WBGene00015742
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in lysosome localization. Predicted to be part of BORC complex. Orthologous to human KXD1 (KxDL motif containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kxd-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (7221469..7222156)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene SAYSvFN domain-containing protein Neighboring gene FTH domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene CCHC-type domain-containing protein Neighboring gene 50S ribosomal protein L6 Neighboring gene ncRNA Neighboring gene peptidylprolyl isomerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8. Niwa S, et al. Curr Biol, 2017 Sep 11. PMID 28823680, Free PMC Article
    2. A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes. Fazeli G, et al. Curr Biol, 2023 Feb 27. PMID 36652947, Free PMC Article
    3. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
    4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lysosome localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of BORC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    KxDL domain-containing protein
    NP_504831.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7221469..7222156
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072430.4 → NP_504831.1  KxDL domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504831.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01488
      Conserved Domains (1) summary
      pfam10241
      Location:39 → 117
      KxDL; Uncharacterized conserved protein
    Nucleotide Protein
    Heading Accession and Version

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