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    tcc-1 Ribosome-binding protein 1 [ Caenorhabditis elegans ]

    Gene ID: 180167, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tcc-1
    Official Full Name
    Ribosome-binding protein 1
    Primary source
    WormBase:WBGene00013340
    Locus tag
    CELE_Y59A8A.3
    See related
    AllianceGenome:WB:WBGene00013340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables kinesin binding activity. Involved in spindle localization. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tcc-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (17845736..17855989, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Serpentine Receptor, class H Neighboring gene COP9 signalosome complex subunit 1 Neighboring gene SAM-dependent methyltransferase Neighboring gene PHD-type domain-containing protein Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. F-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo. Berends CW, et al. Mol Biol Cell, 2013 Jul. PMID 23699393, Free PMC Article
    2. UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration. Fridolfsson HN, et al. Dev Biol, 2010 Feb 15. PMID 20005871, Free PMC Article
    3. RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans. Akay A, et al. Open Biol, 2013 Nov 20. PMID 24258276, Free PMC Article
    4. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article
    5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. F-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the C. elegans embryo.
      Title: F-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables kinesin binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in spindle localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ribosome-binding protein 1
    NP_507506.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      17845736..17855989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075105.6 → NP_507506.1  Ribosome-binding protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507506.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GRZ9
      Conserved Domains (1) summary
      TIGR02169
      Location:178 → 547
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    Nucleotide Protein
    Heading Accession and Version

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