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    srbc-66 Serpentine Receptor, class BC (Class B-like) [ Caenorhabditis elegans ]

    Gene ID: 188824, updated on 9-Dec-2024

    Summary

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    Official Symbol
    srbc-66
    Official Full Name
    Serpentine Receptor, class BC (Class B-like)
    Primary source
    WormBase:WBGene00020746
    Locus tag
    CELE_T24A6.5
    See related
    AllianceGenome:WB:WBGene00020746
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and dauer larval development. Located in non-motile cilium and periciliary membrane compartment. Is expressed in ASKL and ASKR. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See srbc-66 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (3530703..3532380)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene NADAR domain-containing protein Neighboring gene Seven TM Receptor Neighboring gene Nuclear Hormone Receptor family Neighboring gene Nuclear Hormone Receptor family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting. Hu X, et al. Nat Microbiol, 2024 Jul. PMID 38877225, Free PMC Article
    2. Olfactory plasticity is regulated by pheromonal signaling in Caenorhabditis elegans. Yamada K, et al. Science, 2010 Sep 24. PMID 20929849, Free PMC Article
    3. Population Density Modulates the Duration of Reproduction of C. elegans. Wong SS, et al. Curr Biol, 2020 Jul 6. PMID 32442457, Free PMC Article
    4. Two chemoreceptors mediate developmental effects of dauer pheromone in C. elegans. Kim K, et al. Science, 2009 Nov 13. PMID 19797623, Free PMC Article
    5. CREB mediates the C. elegans dauer polyphenism through direct and cell-autonomous regulation of TGF-β expression. Park J, et al. PLoS Genet, 2021 Jul. PMID 34260587, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in dauer larval development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in olfactory learning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in non-motile cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in non-motile cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in periciliary membrane compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in periciliary membrane compartment IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Serpentine Receptor, class BC (Class B-like)
    NP_503986.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      3530703..3532380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071585.1 → NP_503986.1  Serpentine Receptor, class BC (Class B-like) [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503986.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61938
      Conserved Domains (1) summary
      pfam10316
      Location:1 → 272
      7TM_GPCR_Srbc; Serpentine type 7TM GPCR chemoreceptor Srbc
    Nucleotide Protein
    Heading Accession and Version

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