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    dsb-3 Double-Strand Break factor [ Caenorhabditis elegans ]

    Gene ID: 183499, updated on 18-Sep-2024

    Summary

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    Official Symbol
    dsb-3
    Official Full Name
    Double-Strand Break factor
    Primary source
    WormBase:WBGene00016701
    Locus tag
    CELE_C46A5.5
    See related
    AllianceGenome:WB:WBGene00016701
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
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    Genomic context

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    See dsb-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (7757510..7759627, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Peroxidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Acid-sensing ion channel 1-like Neighboring gene Tyrosine-protein phosphatase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans DSB-3 reveals conservation and divergence among protein complexes promoting meiotic double-strand breaks. Hinman AW, et al. Proc Natl Acad Sci U S A, 2021 Aug 17. PMID 34389685, Free PMC Article
    2. Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity. Guo H, et al. Elife, 2022 Jun 27. PMID 35758641, Free PMC Article
    3. Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line. Li Q, et al. PLoS Genet, 2023 Jan. PMID 36716349, Free PMC Article
    4. PARG and BRCA1-BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis. Trivedi S, et al. Nucleic Acids Res, 2022 Nov 28. PMID 36478097, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    General protein information

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    Preferred Names
    Double-Strand Break factor
    NP_001255306.1
    • Product from WormBase gene class dsb;
      Confirmed by transcript evidence
    NP_001255307.1
    • Product from WormBase gene class dsb;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7757510..7759627 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268377.3 → NP_001255306.1  Double-Strand Break factor [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255306.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18649

    2. NM_001268378.1 → NP_001255307.1  Double-Strand Break factor [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255307.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4S5K3
    Nucleotide Protein
    Heading Accession and Version

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