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    mul-1 ShKT domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186063, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mul-1
    Official Full Name
    ShKT domain-containing protein
    Primary source
    WormBase:WBGene00018646
    Locus tag
    CELE_F49F1.6
    See related
    AllianceGenome:WB:WBGene00018646
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in response to gamma radiation. Is expressed in intestinal cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mul-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (4121342..4123166, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ShKT domain-containing protein Neighboring gene ShKT domain-containing protein Neighboring gene ShKT domain-containing protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Host Mucin Is Exploited by Pseudomonas aeruginosa To Provide Monosaccharides Required for a Successful Infection. Hoffman CL, et al. mBio, 2020 Mar 3. PMID 32127446, Free PMC Article
    2. Innate immune genes including a mucin-like gene, mul-1, induced by ionizing radiation in Caenorhabditis elegans. Kimura T, et al. Radiat Res, 2012 Oct. PMID 22967128
    3. The DNA damage-inducible C. elegans tankyrase is a nuclear protein closely linked to chromosomes. White C, et al. Mol Cell Biochem, 2009 Apr. PMID 19104912
    4. Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection. Pukkila-Worley R, et al. PLoS Genet, 2012. PMID 22719261, Free PMC Article
    5. Transcriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family. Greiss S, et al. BMC Genomics, 2008 Jul 15. PMID 18627611, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to gamma radiation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ShKT domain-containing protein
    NP_001299956.1
    • Confirmed by transcript evidence
    NP_500487.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      4121342..4123166 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068086.6 → NP_500487.2  ShKT domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500487.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GZE3
      Conserved Domains (1) summary
      pfam01549
      Location:221 → 259
      ShK; ShK domain-like

    2. NM_001313027.3 → NP_001299956.1  ShKT domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AV21
      Conserved Domains (1) summary
      pfam01549
      Location:151 → 189
      ShK; ShK domain-like
    Nucleotide Protein
    Heading Accession and Version

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