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    F42F12.4 Acireductone dioxygenase [ Caenorhabditis elegans ]

    Gene ID: 181393, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F42F12.4
    Official Full Name
    Acireductone dioxygenase
    Primary source
    WormBase:WBGene00009636
    Locus tag
    CELE_F42F12.4
    See related
    AllianceGenome:WB:WBGene00009636
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acireductone dioxygenase [iron(II)-requiring] activity. Predicted to be involved in methionine metabolic process. Predicted to be located in cytoplasm and nucleus. Orthologous to human ADI1 (acireductone dioxygenase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F42F12.4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (12351995..12352947, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Cysteine-rich transmembrane CYSTM domain-containing protein Neighboring gene 3-oxo-5-alpha-steroid 4-dehydrogenase Neighboring gene pseudo Neighboring gene Nematode Specific Peptide family, group C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acireductone dioxygenase (Ni2+-requiring) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acireductone dioxygenase [iron(II)-requiring] activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables acireductone dioxygenase [iron(II)-requiring] activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nickel cation binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-methionine salvage from methylthioadenosine IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in methionine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in methionine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Acireductone dioxygenase
    NP_510072.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      12351995..12352947 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077671.6 → NP_510072.1  Acireductone dioxygenase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510072.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20340, Q20341
      Conserved Domains (1) summary
      pfam03079
      Location:1 → 156
      ARD; ARD/ARD' family
    Nucleotide Protein
    Heading Accession and Version

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