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    spp-18 Saposin B-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185015, updated on 9-Dec-2024

    Summary

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    Official Symbol
    spp-18
    Official Full Name
    Saposin B-type domain-containing protein
    Primary source
    WormBase:WBGene00005003
    Locus tag
    CELE_F27C8.4
    See related
    AllianceGenome:WB:WBGene00005003
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See spp-18 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (9593712..9594413)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Alpha/beta hydrolase fold-3 domain-containing protein Neighboring gene BTB domain-containing protein Neighboring gene T2SSG domain-containing protein Neighboring gene N-acetyltransferase domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Immunomodulatory effect of pentagalloyl glucose in LPS-stimulated RAW264.7 macrophages and PAO1-induced Caenorhabditis elegans. Zhang X, et al. Exp Gerontol, 2021 Jul 15. PMID 33957261
    2. Signaling in the immune response. Ewbank JJ. WormBook, 2006 Jan 23. PMID 18050470, Free PMC Article
    3. Responses to infection and possible recognition strategies in the innate immune system of Caenorhabditis elegans. Nicholas HR, et al. Mol Immunol, 2004 Jul. PMID 15183927
    4. Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans. Kwon JY, et al. Genomics, 2004 Apr. PMID 15028283
    5. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 

    General protein information

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    Preferred Names
    Saposin B-type domain-containing protein
    NP_001293972.1
    • Confirmed by transcript evidence
    NP_501704.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      9593712..9594413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069303.6 → NP_501704.1  Saposin B-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501704.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19837
      Conserved Domains (1) summary
      smart00741
      Location:48 → 117
      SapB; Saposin (B) Domains

    2. NM_001307043.3 → NP_001293972.1  Saposin B-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293972.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AKY5
      Conserved Domains (1) summary
      smart00741
      Location:14 → 83
      SapB; Saposin (B) Domains
    Nucleotide Protein
    Heading Accession and Version

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