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    ipla-7 PNPLA domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177869, updated on 9-Dec-2024

    Summary

    Official Symbol
    ipla-7
    Official Full Name
    PNPLA domain-containing protein
    Primary source
    WormBase:WBGene00011423
    Locus tag
    CELE_T04B2.5
    See related
    AllianceGenome:WB:WBGene00011423
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium-independent phospholipase A2 activity and long-chain fatty acyl-CoA hydrolase activity. Predicted to be involved in positive regulation of ceramide biosynthetic process. Predicted to be active in mitochondrion. Is expressed in intestine; pharyngeal-intestinal valve; pharynx; virL; and virR. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ipla-7 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (10056591..10059178, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene ncRNA Neighboring gene DUF2780 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein Wnt-2 Neighboring gene MFS domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium-independent phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium-independent phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables long-chain fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of ceramide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    PNPLA domain-containing protein
    NP_001369902.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10056591..10059178 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383178.1NP_001369902.1  PNPLA domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EF58
      Conserved Domains (1) summary
      cl11396
      Location:141442
      Patatin_and_cPLA2; Patatins and Phospholipases