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    tmem-145 GPR180/TMEM145 transmembrane domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182623, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tmem-145
    Official Full Name
    GPR180/TMEM145 transmembrane domain-containing protein
    Primary source
    WormBase:WBGene00007595
    Locus tag
    CELE_C15A7.2
    See related
    AllianceGenome:WB:WBGene00007595
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in membrane. Orthologous to human TMEM145 (transmembrane protein 145). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tmem-145 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    14
    Sequence:
    Chromosome: X; NC_003284.9 (12070631..12073864, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to pheromone IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GPR180/TMEM145 transmembrane domain-containing protein
    NP_510017.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      12070631..12073864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077616.6 → NP_510017.3  GPR180/TMEM145 transmembrane domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510017.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18000
      Conserved Domains (1) summary
      pfam10192
      Location:173 → 429
      GpcrRhopsn4; Rhodopsin-like GPCR transmembrane domain
    Nucleotide Protein
    Heading Accession and Version

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