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    F40F8.11 NADAR domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 4926894, updated on 4-Jan-2025

    Summary

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    Official Symbol
    F40F8.11
    Official Full Name
    NADAR domain-containing protein
    Primary source
    WormBase:WBGene00044916
    Locus tag
    CELE_F40F8.11
    See related
    AllianceGenome:WB:WBGene00044916
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be part of several cellular components, including pICln-Sm protein complex; spliceosomal complex; and spliceosomal snRNP complex. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See F40F8.11 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (11130689..11132590, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene UMP-CMP kinase;UMP-CMP kinase 2 Neighboring gene Transmembrane protein 42 Neighboring gene Uncharacterized protein Neighboring gene Expressed conserved protein;Filaggrin-like;Secreted protein Neighboring gene Fatty-acid and retinol-binding protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of proteins and miRNAs that specifically bind an mRNA in vivo. Theil K, et al. Nat Commun, 2019 Sep 16. PMID 31527589, Free PMC Article
    2. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Zinovyeva AY, et al. Proc Natl Acad Sci U S A, 2015 Sep 22. PMID 26351692, Free PMC Article
    3. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    4. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    5. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in spliceosomal snRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SMN-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of commitment complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of pICln-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NADAR domain-containing protein
    NP_001254278.1
    • Confirmed by transcript evidence
    NP_001254279.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11130689..11132590 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267349.4 → NP_001254278.1  NADAR domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254278.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0G828
      Conserved Domains (1) summary
      cd15457
      Location:227 → 425
      NADAR; Escherichia coli swarming motility protein YbiA and related proteins

    2. NM_001267350.3 → NP_001254279.1  NADAR domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254279.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L297
      Conserved Domains (1) summary
      cd15457
      Location:81 → 279
      NADAR; Escherichia coli swarming motility protein YbiA and related proteins
    Nucleotide Protein
    Heading Accession and Version

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