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    cnc-6 CaeNaCin (Caenorhabditis bacteriocin) [ Caenorhabditis elegans ]

    Gene ID: 175324, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cnc-6
    Official Full Name
    CaeNaCin (Caenorhabditis bacteriocin)
    Primary source
    WormBase:WBGene00000560
    Locus tag
    CELE_Y46E12A.1
    See related
    AllianceGenome:WB:WBGene00000560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to fungus and innate immune response. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cnc-6 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003281.10 (1763522..1764902)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene DUF72 domain-containing protein Neighboring gene T-box domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A pair of RNA binding proteins inhibit ion transporter expression to maintain lifespan. Napier-Jameson R, et al. Genetics, 2024 Feb 7. PMID 38112749,
    2. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Couillault C, et al. Nat Immunol, 2004 May. PMID 15048112
    3. Anti-fungal innate immunity in C. elegans is enhanced by evolutionary diversification of antimicrobial peptides. Pujol N, et al. PLoS Pathog, 2008 Jul 18. PMID 18636113, Free PMC Article
    4. Innate Immunity Promotes Sleep through Epidermal Antimicrobial Peptides. Sinner MP, et al. Curr Biol, 2021 Feb 8. PMID 33259791
    5. Evolution of the innate immune system: the worm perspective. Schulenburg H, et al. Immunol Rev, 2004 Apr. PMID 15199953

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in defense response to fungus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in innate immune response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CaeNaCin (Caenorhabditis bacteriocin)
    NP_497455.1
    • Product from WormBase gene class cnc;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1763522..1764902
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065054.4 → NP_497455.1  CaeNaCin (Caenorhabditis bacteriocin) [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497455.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3V6
    Nucleotide Protein
    Heading Accession and Version

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