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    sql-1 GRIP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190949, updated on 9-Dec-2024

    Summary

    Official Symbol
    sql-1
    Official Full Name
    GRIP domain-containing protein
    Primary source
    WormBase:WBGene00013730
    Locus tag
    CELE_Y111B2A.4
    See related
    AllianceGenome:WB:WBGene00013730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in Golgi organization and endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus. Human ortholog(s) of this gene implicated in achondrogenesis type IA. Orthologous to human TRIP11 (thyroid hormone receptor interactor 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See sql-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    19
    Sequence:
    Chromosome: III; NC_003281.10 (12499557..12528052)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Mitochondrial cytochrome c oxidase subunit VIc/VIIs domain-containing protein Neighboring gene Helicase sen1 Neighboring gene pseudo Neighboring gene pseudo Neighboring gene CBS domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables small GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    GRIP domain-containing protein
    NP_001255174.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      12499557..12528052
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268245.3NP_001255174.1  GRIP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255174.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0Z5P0
      Conserved Domains (1) summary
      COG1196
      Location:3941184
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. NR_052807.1 RNA Sequence

      Status: REVIEWED