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    ctg-2 CRAL-TRIO domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174360, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ctg-2
    Official Full Name
    CRAL-TRIO domain-containing protein
    Primary source
    WormBase:WBGene00011756
    Locus tag
    CELE_T13H5.2
    See related
    AllianceGenome:WB:WBGene00011756
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in cytoplasm. Orthologous to several human genes including SEC14L2 (SEC14 like lipid binding 2); SEC14L3 (SEC14 like lipid binding 3); and SEC14L4 (SEC14 like lipid binding 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ctg-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (8515054..8516922)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein Neighboring gene ncRNA Neighboring gene DB domain-containing protein Neighboring gene Ribonuclease H2 subunit A Neighboring gene Lipid scramblase CLPTM1L

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CRAL-TRIO domain-containing protein
    NP_001254156.1
    • Partially confirmed by transcript evidence
    NP_001367210.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8515054..8516922
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267227.3 → NP_001254156.1  CRAL-TRIO domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254156.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22467
      Conserved Domains (2) summary
      smart00516
      Location:98 → 267
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
      pfam01105
      Location:331 → 405
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD

    2. NM_001381528.1 → NP_001367210.1  CRAL-TRIO domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7WN92
      Conserved Domains (2) summary
      smart00516
      Location:86 → 255
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
      pfam01105
      Location:319 → 393
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD
    Nucleotide Protein
    Heading Accession and Version

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