T13H5.1 Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: T13H5.1
Official Full Name: Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein
Primary source: WormBase:WBGene00011755
Locus tag: CELE_T13H5.1
See related: AllianceGenome:WB:WBGene00011755
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in signal transduction and synaptic membrane adhesion. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A) and PTPRE (protein tyrosine phosphatase receptor type E). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See T13H5.1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 28

Sequence:: Chromosome: II; NC_003280.10 (8487513..8509056, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

T13H5.1 (e-PCR)
- UniSTS:320352

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein

NP_001022346.2

Confirmed by transcript evidence

NP_001022347.1

Confirmed by transcript evidence

NP_001122640.1

Confirmed by transcript evidence

NP_001129824.1

Confirmed by transcript evidence

NP_001129825.1

Partially confirmed by transcript evidence

NP_001254153.1

Confirmed by transcript evidence

NP_001254154.1

Confirmed by transcript evidence

NP_001254155.1

Confirmed by transcript evidence

NP_001379493.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

8487513..8509056 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001027175.4 → NP_001022346.2 Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022346.2

Status: REVIEWED

UniProtKB/TrEMBL

G5EGI0

Conserved Domains (2) summary

smart00194
Location:206 → 465

PTPc; Protein tyrosine phosphatase, catalytic domain

cd00047
Location:233 → 465

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
NM_001136352.5 → NP_001129824.1 Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001129824.1

Status: REVIEWED

UniProtKB/TrEMBL

G5EGJ3

Conserved Domains (2) summary

smart00194
Location:93 → 352

PTPc; Protein tyrosine phosphatase, catalytic domain

cd00047
Location:120 → 352

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
NM_001136353.3 → NP_001129825.1 Receptor-type tyrosine-protein phosphatase mu [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001129825.1

Status: REVIEWED

UniProtKB/TrEMBL

G5EGM6

Conserved Domains (2) summary

smart00194
Location:66 → 325

PTPc; Protein tyrosine phosphatase, catalytic domain

cd00047
Location:93 → 325

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
NM_001129168.4 → NP_001122640.1 Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001122640.1

Status: REVIEWED

UniProtKB/TrEMBL

G5EC69

Conserved Domains (3) summary

smart00194
Location:206 → 465

PTPc; Protein tyrosine phosphatase, catalytic domain

cd00047
Location:233 → 465

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

cl21483
Location:528 → 796

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
NM_001267225.3 → NP_001254154.1 Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001254154.1

Status: REVIEWED

UniProtKB/TrEMBL

G5ECI6

Conserved Domains (2) summary

smart00194
Location:162 → 421

PTPc; Protein tyrosine phosphatase, catalytic domain

cd00047
Location:189 → 421

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
NM_001393137.1 → NP_001379493.1 Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

G5EEM4

Conserved Domains (1) summary

smart00194
Location:155 → 414

PTPc; Protein tyrosine phosphatase, catalytic domain
NM_001267226.3 → NP_001254155.1 Receptor-type tyrosine-protein phosphatase mu [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001254155.1

Status: REVIEWED

UniProtKB/TrEMBL

G5EG42

Conserved Domains (2) summary

smart00194
Location:57 → 316

PTPc; Protein tyrosine phosphatase, catalytic domain

cd00047
Location:84 → 316

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
NM_001027176.5 → NP_001022347.1 Receptor-type tyrosine-protein phosphatase kappa [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022347.1

Status: REVIEWED

UniProtKB/TrEMBL

G5EFE8

Conserved Domains (2) summary

smart00194
Location:114 → 373

PTPc; Protein tyrosine phosphatase, catalytic domain

cd00047
Location:141 → 373

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
NM_001267224.3 → NP_001254153.1 Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001254153.1

Status: REVIEWED

UniProtKB/TrEMBL

F5GU90

Conserved Domains (1) summary

cl21483
Location:25 → 127

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...