aakg-5 CBS domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: aakg-5
Official Full Name: CBS domain-containing protein
Primary source: WormBase:WBGene00011276
Locus tag: CELE_R53.7
See related: AllianceGenome:WB:WBGene00011276
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be involved in cellular response to glucose starvation; regulation of carbohydrate metabolic process; and regulation of carbon utilization. Predicted to be part of nucleotide-activated protein kinase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including epithelial cell; excretory cell; hermaphrodite gonad; neurons; and rectal epithelium. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See aakg-5 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 5

Sequence:: Chromosome: II; NC_003280.10 (9971050..9974704, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R53.7 (e-PCR)
- UniSTS:310580

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CBS domain-containing protein

NP_496155.1

Confirmed by transcript evidence

NP_871971.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

9971050..9974704 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_182171.4 → NP_871971.1 CBS domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_871971.1

Status: REVIEWED

UniProtKB/TrEMBL

Q8I112

Conserved Domains (4) summary

COG0517
Location:257 → 374

CBS; CBS domain [Signal transduction mechanisms]

cd02205
Location:330 → 448

CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...

cd04618
Location:184 → 300

CBS_pair_5; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...

cd04621
Location:256 → 377

CBS_pair_8; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...
NM_063754.6 → NP_496155.1 CBS domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_496155.1

Status: REVIEWED

UniProtKB/TrEMBL

Q22022

Conserved Domains (4) summary

COG0517
Location:229 → 346

CBS; CBS domain [Signal transduction mechanisms]

cd02205
Location:302 → 420

CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...

cd04618
Location:156 → 272

CBS_pair_5; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...

cd04621
Location:228 → 349

CBS_pair_8; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...