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    ztf-7 Zinc finger protein ztf-7 [ Caenorhabditis elegans ]

    Gene ID: 179375, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ztf-7
    Official Full Name
    Zinc finger protein ztf-7
    Primary source
    WormBase:WBGene00009772
    Locus tag
    CELE_F46B6.7
    See related
    AllianceGenome:WB:WBGene00009772
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm. Is expressed in several structures, including anal region; body wall musculature; digestive tract; nerve ring; and reproductive system. Orthologous to human ZNF277 (zinc finger protein 277). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ztf-7 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (9786993..9789707, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene LisH domain-containing protein Neighboring gene Tr-type G domain-containing protein Neighboring gene ncRNA Neighboring gene Lipase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans. Jovanovic M, et al. Nat Methods, 2010 Oct. PMID 20835247, Free PMC Article
    2. A ZTF-7/RPS-2 complex mediates the cold-warm response in C. elegans. Xu T, et al. PLoS Genet, 2023 Feb. PMID 36763670, Free PMC Article
    3. A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target. Andachi Y. RNA, 2008 Nov. PMID 18824511, Free PMC Article
    4. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
    5. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A ZTF-7/RPS-2 complex mediates the cold-warm response in C. elegans.
      Title: A ZTF-7/RPS-2 complex mediates the cold-warm response in C. elegans.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Zinc finger protein ztf-7
    NP_505526.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9786993..9789707 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073125.7 → NP_505526.1  Zinc finger protein ztf-7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505526.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20448
      Conserved Domains (3) summary
      PTZ00108
      Location:1 → 152
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      sd00020
      Location:358 → 380
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12756
      Location:307 → 394
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q20448.1

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