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    Y17G7B.17 Myeloid leukemia factor [ Caenorhabditis elegans ]

    Gene ID: 174849, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y17G7B.17
    Official Full Name
    Myeloid leukemia factor
    Primary source
    WormBase:WBGene00012468
    Locus tag
    CELE_Y17G7B.17
    See related
    AllianceGenome:WB:WBGene00012468
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in cytoplasm and nucleus. Orthologous to several human genes including MLF2 (myeloid leukemia factor 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y17G7B.17 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (12092419..12099989, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene ANK_REP_REGION domain-containing protein;Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2;Truncated ctn-1 Neighboring gene putative RNA methyltransferase Y17G7B.18 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Myeloid leukemia factor
    NP_496571.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12092419..12099989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064170.9 → NP_496571.2  Myeloid leukemia factor [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496571.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXH7
      Conserved Domains (1) summary
      pfam10248
      Location:53 → 193
      Mlf1IP; Myelodysplasia-myeloid leukemia factor 1-interacting protein
    Nucleotide Protein
    Heading Accession and Version

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