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    plin-1 Perilipin-1 homolog [ Caenorhabditis elegans ]

    Gene ID: 172437, updated on 9-Dec-2024

    Summary

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    Official Symbol
    plin-1
    Official Full Name
    Perilipin-1 homolog
    Primary source
    WormBase:WBGene00007024
    Locus tag
    CELE_W01A8.1
    See related
    AllianceGenome:WB:WBGene00007024
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in embryo development. Predicted to be located in lipid droplet. Is expressed in germ line; hypodermal cell; and intestinal cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See plin-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (7057192..7059351)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene DUF19 domain-containing protein Neighboring gene UPF0235 protein Neighboring gene pseudo Neighboring gene ZP domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Perilipin-related protein regulates lipid metabolism in C. elegans. Chughtai AA, et al. PeerJ, 2015. PMID 26357594, Free PMC Article
    2. Caenorhabditis elegans Perilipin Is Implicated in Cold-Induced Lipolysis and Inhibits Autophagy in Early Embryos. Kassak F, et al. Folia Biol (Praha), 2020. PMID 34087974
    3. A Flexible Network of Lipid Droplet Associated Proteins Support Embryonic Integrity of C. elegans. Cao Z, et al. Front Cell Dev Biol, 2022. PMID 35445028, Free PMC Article
    4. Systematic, RNA-interference-mediated identification of mus-101 modifier genes in Caenorhabditis elegans. Holway AH, et al. Genetics, 2005 Mar. PMID 15654100, Free PMC Article
    5. Proteomic Interactome of C. elegans Mediator Complex Subunit 28 (MDT-28) Reveals Predominant Association with a Restricted Set of Core Mediator Subunits and an Affinity to Additional Structural and Enzymatic Proteins. Yilma P, et al. Folia Biol (Praha), 2019. PMID 32362303

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in embryo development ending in birth or egg hatching IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Perilipin-1 homolog
    NP_001021646.1
    • Confirmed by transcript evidence
    NP_001021647.1
    • Confirmed by transcript evidence
    NP_001122526.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7057192..7059351
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129054.5 → NP_001122526.1  Perilipin-1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122526.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8WHP8, Q23095, Q65ZB1
      Conserved Domains (1) summary
      pfam11594
      Location:246 → 376
      Med28; Mediator complex subunit 28

    2. NM_001026475.4 → NP_001021646.1  Perilipin-1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021646.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8WHP8
      Conserved Domains (2) summary
      pfam03036
      Location:35 → 69
      Perilipin; Perilipin family
      pfam11594
      Location:243 → 372
      Med28; Mediator complex subunit 28

    3. NM_001026476.5 → NP_001021647.1  Perilipin-1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021647.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8WHP8
      Conserved Domains (2) summary
      pfam03036
      Location:35 → 69
      Perilipin; Perilipin family
      pfam11594
      Location:243 → 372
      Med28; Mediator complex subunit 28
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8WHP8.1

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