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    kin-16 Receptor-like tyrosine-protein kinase kin-16 [ Caenorhabditis elegans ]

    Gene ID: 174499, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kin-16
    Official Full Name
    Receptor-like tyrosine-protein kinase kin-16
    Primary source
    WormBase:WBGene00002200
    Locus tag
    CELE_M176.7
    See related
    AllianceGenome:WB:WBGene00002200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in hyp6 and hyp7 syncytium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kin-16 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (9434021..9436109, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein;Receptor-like tyrosine-protein kinase kin-15 Neighboring gene GH18 domain-containing protein Neighboring gene GH18 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms. Plowman GD, et al. Proc Natl Acad Sci U S A, 1999 Nov 23. PMID 10570119, Free PMC Article
    2. Two novel transmembrane protein tyrosine kinases expressed during Caenorhabditis elegans hypodermal development. Morgan WR, et al. Mol Cell Biol, 1993 Nov. PMID 8413302, Free PMC Article
    3. A PAX6-regulated receptor tyrosine kinase pairs with a pseudokinase to activate immune defense upon oomycete recognition in Caenorhabditis elegans. Drury F, et al. Proc Natl Acad Sci U S A, 2023 Sep 26. PMID 37725647, Free PMC Article
    4. The family of Caenorhabditis elegans tyrosine kinase receptors: similarities and differences with mammalian receptors. Popovici C, et al. Genome Res, 1999 Nov. PMID 10568743
    5. Paralogy and orthology of tyrosine kinases that can extend the life span of Caenorhabditis elegans. Rikke BA, et al. Mol Biol Evol, 2000 May. PMID 10779528

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane receptor protein tyrosine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in multicellular organism development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Receptor-like tyrosine-protein kinase kin-16
    NP_496017.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9434021..9436109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063616.7 → NP_496017.1  Receptor-like tyrosine-protein kinase kin-16 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496017.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34892
      Conserved Domains (2) summary
      smart00221
      Location:140 → 454
      STYKc; Protein kinase; unclassified specificity
      cd00192
      Location:145 → 454
      PTKc; Catalytic domain of Protein Tyrosine Kinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34892.1

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