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    plp-2 DUF3467 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 184719, updated on 4-Jan-2025

    Summary

    Official Symbol
    plp-2
    Official Full Name
    DUF3467 domain-containing protein
    Primary source
    WormBase:WBGene00008976
    Locus tag
    CELE_F20D1.4
    See related
    AllianceGenome:WB:WBGene00008976
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and purine-rich negative regulatory element binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human PURB (purine rich element binding protein B) and PURG (purine rich element binding protein G). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See plp-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    2
    Sequence:
    Chromosome: X; NC_003284.9 (14982140..14982804, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Essential MCU regulator, mitochondrial Neighboring gene pseudo Neighboring gene Rab3 GTPase-activating protein catalytic subunit Neighboring gene Ig-like domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DUF3467 domain-containing protein
    NP_510489.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14982140..14982804 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078088.3NP_510489.1  DUF3467 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510489.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93537
      Conserved Domains (1) summary
      smart00712
      Location:100171
      PUR; DNA/RNA-binding repeats in PUR-alpha/beta/gamma and in hypothetical proteins from spirochetes and the Bacteroides-Cytophaga-Flexibacter bacteria