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    nhr-18 Nuclear hormone receptor family member nhr-18 [ Caenorhabditis elegans ]

    Gene ID: 178702, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhr-18
    Official Full Name
    Nuclear hormone receptor family member nhr-18
    Primary source
    WormBase:WBGene00003617
    Locus tag
    CELE_F44C8.3
    See related
    AllianceGenome:WB:WBGene00003617
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in anal depressor muscle; intestinal muscle; and vulval muscle. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nhr-18 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (2227203..2228986)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Nuclear Hormone Receptor family Neighboring gene Nuclear hormone receptor family member nhr-103 Neighboring gene Nuclear Hormone Receptor family Neighboring gene Nuclear hormone receptor family member nhr-134

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear hormone receptor family member nhr-18
    NP_503608.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      2227203..2228986
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071207.7 → NP_503608.2  Nuclear hormone receptor family member nhr-18 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503608.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O16360, Q9XYC0
      Conserved Domains (2) summary
      pfam00104
      Location:163 → 371
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor
      cl02596
      Location:11 → 86
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O16360.3

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