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    ani-3 Anillin-like protein 3 [ Caenorhabditis elegans ]

    Gene ID: 180291, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ani-3
    Official Full Name
    Anillin-like protein 3
    Primary source
    WormBase:WBGene00012835
    Locus tag
    CELE_Y43F8C.14
    See related
    AllianceGenome:WB:WBGene00012835
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in actomyosin contractile ring assembly; mitotic cytokinesis; and septin ring organization. Predicted to be active in actomyosin contractile ring. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Orthologous to human ANLN (anillin, actin binding protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ani-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (19697732..19705212)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Multidrug resistance protein mrp-7 Neighboring gene Nucleoside hydrolase Neighboring gene ncRNA Neighboring gene Serpentine receptor class gamma Neighboring gene DUF281 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinct roles for two C. elegans anillins in the gonad and early embryo. Maddox AS, et al. Development, 2005 Jun. PMID 15930113
    2. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in actomyosin contractile ring assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in septin ring organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actomyosin contractile ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Anillin-like protein 3
    NP_507814.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      19697732..19705212
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075413.5 → NP_507814.1  Anillin-like protein 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507814.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XWN6
      Conserved Domains (3) summary
      cd01263
      Location:584 → 708
      PH_anillin; Anillin Pleckstrin homology (PH) domain
      pfam00169
      Location:586 → 704
      PH; PH domain
      pfam08174
      Location:407 → 552
      Anillin; Cell division protein anillin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XWN6.1

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